Affected Twins in the Familial Intracranial Aneurysm Study | Zendy

Jason Mackey | Zendy; Robert D. Brown | Zendy; Laura Sauerbeck | Zendy; Richard Hornung | Zendy; Charles J. Moomaw | Zendy; Daniel L. Koller | Zendy; Tatiana Foroud | Zendy; Ranjan Deka | Zendy; Daniel Woo | Zendy; Dawn Kleindorfer | Zendy; Matthew L. Flaherty | Zendy; Irene Meissner | Zendy; Craig S. Anderson | Zendy; Guy A. Rouleau | Zendy; E. Sander Connolly | Zendy; John Huston | Zendy; Joseph P. Broderick | Zendy

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Affected Twins in the Familial Intracranial Aneurysm Study

Author(s) -

Jason Mackey,

Robert D. Brown,

Laura Sauerbeck,

Richard Hornung,

Charles J. Moomaw,

Daniel L. Koller,

Tatiana Foroud,

Ranjan Deka,

Daniel Woo,

Dawn Kleindorfer,

Matthew L. Flaherty,

Irene Meissner,

Craig S. Anderson,

Guy A. Rouleau,

E. Sander Connolly,

John Huston,

Joseph P. Broderick

Publication year - 2015

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000369961

Subject(s) - medicine , concordance , zygosity , monozygotic twin , aneurysm , porencephaly , twin study , polymicrogyria , pediatrics , cardiology , surgery , heritability , pathology , genetics , magnetic resonance imaging , radiology , biology

Very few cases of intracranial aneurysms (IAs) in twins have been reported. Previous work has suggested that vulnerability to IA formation is heritable. Twin studies provide an opportunity to evaluate the impact of genetics on IA characteristics, including IA location. We therefore sought to examine IA location concordance, multiplicity, and rupture status within affected twin-pairs.

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