Nox4 Is a Major Source of Superoxide Production in Human Brain Pericytes | Zendy

Junya Kuroda | Zendy; Tetsuro Ago | Zendy; Ataru Nishimura | Zendy; Kuniyuki Nakamura | Zendy; Ryu Matsuo | Zendy; Yoshinobu Wakisaka | Zendy; Masahiro Kamouchi | Zendy; Takanari Kitazono | Zendy

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Nox4 Is a Major Source of Superoxide Production in Human Brain Pericytes

Author(s) -

Junya Kuroda,

Tetsuro Ago,

Ataru Nishimura,

Kuniyuki Nakamura,

Ryu Matsuo,

Yoshinobu Wakisaka,

Masahiro Kamouchi,

Takanari Kitazono

Publication year - 2014

Publication title -

journal of vascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.58

H-Index - 74

eISSN - 1423-0135

pISSN - 1018-1172

DOI - 10.1159/000369930

Subject(s) - nox4 , superoxide , reactive oxygen species , superoxide dismutase , nad(p)h oxidase , chemistry , gene silencing , microbiology and biotechnology , nadph oxidase , biology , oxidative stress , biochemistry , enzyme , gene

Pericytes are multifunctional cells surrounding capillaries and postcapillary venules. In brain microvasculature, pericytes play a pivotal role under physiological and pathological conditions by producing reactive oxygen species (ROS). The aims of this study were to elucidate the source of ROS and its regulation in human brain pericytes.

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