PTPRO-Associated Hepatic Stellate Cell Activation Plays a Critical Role in Liver Fibrosis
Author(s) -
Xudong Zhang,
Zhongming Tan,
Youjing Wang,
Junwei Tang,
R Jiang,
Jiajie Hou,
Han Zhuo,
Xiaochen Wang,
Jie Ji,
Xihu Qin,
Beicheng Sun
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000369746
Subject(s) - hepatic stellate cell , hepatic fibrosis , cancer research , fibrosis , biology , protein kinase b , signal transduction , platelet derived growth factor receptor , microbiology and biotechnology , medicine , growth factor , receptor , pathology , endocrinology , biochemistry
PTPRO (protein tyrosine phosphatase, receptor type O) is implicated in diverse physiological and pathological processes in cancer and hepatic ischemia/reperfusion injury, although little is known about its role in hepatic fibrosis.
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