Effects of Three Kinds of Curcuminoids on Anti-Oxidative System and Membrane Deformation of Human Peripheral Blood Erythrocytes in High Glucose Levels | Zendy

Wei Yang | Zendy; Juan Fu | Zendy; Miao Yu | Zendy; Di Wang | Zendy; Rong Ying | Zendy; Ping Yao | Zendy; Andreas K. Nüssler | Zendy; Hong Yan | Zendy; Liegang Liu | Zendy

Open Access

Effects of Three Kinds of Curcuminoids on Anti-Oxidative System and Membrane Deformation of Human Peripheral Blood Erythrocytes in High Glucose Levels

Author(s) -

Wei Yang,

Juan Fu,

Miao Yu,

Di Wang,

Rong Ying,

Ping Yao,

Andreas K. Nüssler,

Hong Yan,

Liegang Liu

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000369738

Subject(s) - malondialdehyde , lipid peroxidation , oxidative stress , chemistry , flow cytometry , biochemistry , phospholipid , membrane , biology , microbiology and biotechnology

Curcuminoids are the main bioactive constituents of the rhizome of turmeric. Erythrocytes lesions in diabetes are probably related to hyperglycemia and protein glycation. It has been reported that curcumin prevent lipid peroxidation. However, reports on the effects of demethoxycurcumin and bis-demethoxycurcumin on human erythrocytes at high glucose levels are scarce. Our aim is to investigate the effect of curcuminoids on oxidative stress and membrane of erythrocytes exposed to hyperglycemic condition.

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