Beta-1-Adrenergic Receptors Mediate Nrf2-HO-1-HMGB1 Axis Regulation to Attenuate Hypoxia/Reoxygenation-Induced Cardiomyocytes Injury in Vitro | Zendy

Jichun Wang | Zendy; Xiaorong Hu | Zendy; Jing Xie | Zendy; Weipan Xu | Zendy; Hong Jiang | Zendy

Open Access

Beta-1-Adrenergic Receptors Mediate Nrf2-HO-1-HMGB1 Axis Regulation to Attenuate Hypoxia/Reoxygenation-Induced Cardiomyocytes Injury in Vitro

Author(s) -

Jichun Wang,

Xiaorong Hu,

Jing Xie,

Weipan Xu,

Hong Jiang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000369736

Subject(s) - hypoxia (environmental) , receptor , in vitro , microbiology and biotechnology , adrenergic receptor , chemistry , pharmacology , beta 3 adrenergic receptor , endocrinology , medicine , biology , biochemistry , organic chemistry , oxygen

BACKGROUD/AIMS: The aim of the study was to evaluate the effects of beta1-adrenergic receptors (β1-ARs) -mediated nuclear factor erythroid 2-related factor 2 (Nrf2)-heme oxygenase-1 (HO-1)-high mobility group box 1 protein (HMGB1) axis regulation in hypoxia/reoxygenation (H/R)-induced neonatal rat cardiomyocytes.

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