Effects of Nicotinamide N-Methyltransferase on PANC-1 Cells Proliferation, Metastatic Potential and Survival Under Metabolic Stress | Zendy

Tao Yu | Zendy; Yongtao Wang | Zendy; Pan Chen | Zendy; Yu-Hua Li | Zendy; Yi-xin Chen | Zendy; Hang Zeng | Zendy; AiMing Yu | Zendy; Min Huang | Zendy; Hui-Chang Bi | Zendy

Open Access

Effects of Nicotinamide N-Methyltransferase on PANC-1 Cells Proliferation, Metastatic Potential and Survival Under Metabolic Stress

Author(s) -

Tao Yu,

Yongtao Wang,

Pan Chen,

Yu-Hua Li,

Yi-xin Chen,

Hang Zeng,

AiMing Yu,

Min Huang,

Hui-Chang Bi

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000369731

Subject(s) - cell growth , gene silencing , biology , cell culture , transfection , cancer research , downregulation and upregulation , matrigel , pancreatic cancer , small interfering rna , cancer cell , gene knockdown , cell , microbiology and biotechnology , cancer , biochemistry , genetics , gene

Aberrant expression of Nicotinamide N-methyltransferase (NNMT) has been reported in pancreatic cancer. However, the role of NNMT in pancreatic cancer development remains elusive. Therefore, the present study was to investigate the impact of NNMT on pancreatic cancer cell proliferation, metastatic potential and survival under metabolic stress.

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