Curcumin Treatment Suppresses CCR7 Expression and the Differentiation and Migration of Human Circulating Fibrocytes | Zendy

Xuyan Fu | Zendy; Dongwei Zhang | Zendy; Yadong Li | Zendy; Pi-wen Zhao | Zendy; Yuqing Tang | Zendy; Jianzhao Niu | Zendy; Yu Li | Zendy

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Curcumin Treatment Suppresses CCR7 Expression and the Differentiation and Migration of Human Circulating Fibrocytes

Author(s) -

Xuyan Fu,

Dongwei Zhang,

Yadong Li,

Pi-wen Zhao,

Yuqing Tang,

Jianzhao Niu,

Yu Li

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000369714

Subject(s) - fibrocyte , curcumin , flow cytometry , c c chemokine receptor type 7 , fibrosis , chemistry , cancer research , microbiology and biotechnology , chemokine , biology , immunology , pharmacology , medicine , chemokine receptor , pathology , immune system

Recent studies have demonstrated that circulating fibrocytes contribute to the formation and development of fibrosis. Curcumin, a polyphenolic compound isolated from turmeric, has been shown to have anti-fibrotic effects in various organs. We and others have demonstrated that curcumin beneficially affects the development of fibrosis. However the effect of curcumin on circulating fibrocytes has not been reported.

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