Open AccessMatrine Inhibits Mouse Sperm Function by Reducing Sperm [Ca2+]i and Phospho-ERK1/2
Author(s) -
Tao Luo,
Qianxing Zou,
Yuanqiao He,
Huafeng Wang,
Na Li,
Xuhui Zeng
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000369703
Subject(s) - sperm , andrology , chemistry , microbiology and biotechnology , function (biology) , sperm motility , biophysics , pharmacology , biology , medicine
Matrine is a bioactive alkaloid that has a variety of pharmacological effects and is widely used in Chinese medicine. However, its effects on male reproduction are not well known. In this study, we aimed to investigate the in vitro toxicity of matrine on mature mouse sperm.
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