Open AccessKnockdown of Polycomb-Group RING Finger 6 Modulates Mouse Male Germ Cell Differentiation in Vitro
Author(s) -
Jin Sun,
Jian Wang,
Lin He,
Yi Lin,
Ji Wu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000369700
Subject(s) - biology , germ cell , microbiology and biotechnology , propidium iodide , gene knockdown , flow cytometry , transcription factor , population , cell cycle , cell , cell culture , apoptosis , genetics , gene , demography , programmed cell death , sociology
Polycomb-group RING finger 6 (PCGF6), one of six PCGF homologs, is the core component of the PRC1 complex that plays critical roles in epigenetic transcriptional silencing in higher eukaryotes. However, the biological functions of PCGF6 are unknown.
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