Midazolam Inhibits the Apoptosis of Astrocytes Induced by Oxygen Glucose Deprivation via Targeting JAK2-STAT3 Signaling Pathway | Zendy

Li Liu | Zendy; Qi You | Zendy; Yingfeng Tu | Zendy; Quanyi Li | Zendy; Lihong Zheng | Zendy; Xuan Li | Zendy; Jing Gu | Zendy; Guonian Wang | Zendy

Open Access

Midazolam Inhibits the Apoptosis of Astrocytes Induced by Oxygen Glucose Deprivation via Targeting JAK2-STAT3 Signaling Pathway

Author(s) -

Li Liu,

Qi You,

Yingfeng Tu,

Quanyi Li,

Lihong Zheng,

Xuan Li,

Jing Gu,

Guonian Wang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000369681

Subject(s) - apoptosis , tunel assay , mtt assay , astrocyte , cell growth , flow cytometry , stat3 , pharmacology , biology , chemistry , microbiology and biotechnology , endocrinology , biochemistry , central nervous system

There is an increasing interest in the role of astrocytes contributing to the intrinsic bioremediation of ischemic brain injury. The purpose of this study was to disclose the effects and mechanism of midazolam (MDZ) on the proliferation and apoptosis of astrocytes under oxygen glucose deprivation (OGD) condition.

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