Association of CD40 -1C/T Polymorphism in the 5′-Untranslated Region with Chronic HBV Infection | Zendy

Cheng Zhou | Zendy; Xiaoli Jin | Zendy; Jie Tang | Zendy; Jiaqian Fei | Zendy; Chunxia Gu | Zendy; Xi Chen | Zendy

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Association of CD40 -1C/T Polymorphism in the 5′-Untranslated Region with Chronic HBV Infection

Author(s) -

Cheng Zhou,

Xiaoli Jin,

Jie Tang,

Jiaqian Fei,

Chunxia Gu,

Xi Chen

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000369677

Subject(s) - single nucleotide polymorphism , genotype , immunology , hepatitis b virus , cd40 , biology , medicine , virology , virus , genetics , gene , cytotoxic t cell , in vitro

CD40 is an important costimulatory molecule in both cellular and humoral immune responses, involved in the pathogenic processes of chronic inflammatory diseases. Few studies were performed on the association of CD40 single nucleotide polymorphism (SNP) with chronic hepatitis B virus (HBV) infection. In this study, we studied whether the CD40-1C/T polymorphism had any effect on the progression of chronic HBV infection in Chinese population.

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