Adenosine Deaminase Inhibitor EHNA Exhibits a Potent Anticancer Effect Against Malignant Pleural Mesothelioma
Author(s) -
Y. Nakajima,
Takeshi Kanno,
Toshio Nagaya,
Kozo Kuribayashi,
Takashi Nakano,
Akinobu Gotoh,
Tomoyuki Nishizaki
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000369674
Subject(s) - ehna , adenosine deaminase , adenosine deaminase inhibitor , apoptosis , adenosine , intracellular , tunel assay , cancer research , chemistry , pharmacology , cell culture , cell growth , medicine , biology , biochemistry , genetics
Malignant pleural mesothelioma (MPM) is an aggressive malignant tumor and an effective therapy has been little provided as yet. The present study investigated the possibility for the adenosine deaminase (ADA) inhibitor EHNA as a target of MPM treatment.
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