Chronic Psychological Distress as an Inducer of Microglial Activation and Leukocyte Recruitment into the Area Postrema | Zendy

Alejandra Vargas-Caraveo | Zendy; David Guillermo Pérez-Ishiwara | Zendy; Alejandro MartínezMartínez | Zendy

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Chronic Psychological Distress as an Inducer of Microglial Activation and Leukocyte Recruitment into the Area Postrema

Author(s) -

Alejandra Vargas-Caraveo,

David Guillermo Pérez-Ishiwara,

Alejandro MartínezMartínez

Publication year - 2015

Publication title -

neuroimmunomodulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.635

H-Index - 65

eISSN - 1423-0216

pISSN - 1021-7401

DOI - 10.1159/000369350

Subject(s) - immune system , microglia , neuroinflammation , integrin alpha m , immunology , inflammation , medicine , biology

Chronic psychological distress can cause neuroinflammation, but the involvement of leukocytes in this inflammatory response remains unclear. The area postrema (AP) is considered a neural-immune interface because it lacks a blood-brain barrier and a site for leukocyte recruitment in neuroinflammatory conditions induced by immunological insults, but its role in chronic psychological distress has not been explored.

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