Genotyping of CCR5 Gene, CCR2b and SDF1 Variants Related to HIV-1 Infection in Gabonese Subjects
Author(s) -
Landry Erik Mombo,
Cyrille Bisseyé,
Patrick Mickala,
Simon Ossari,
Maria Makuwa
Publication year - 2015
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000369016
Subject(s) - genotyping , human immunodeficiency virus (hiv) , genetics , gene , biology , polymerase chain reaction , virology , genotype
Given the magnitude of the HIV epidemic infection, many viral and human factors were analyzed, and the most decisive was the variant CCR5-Δ32. The presence of a low HIV prevalence (1.8%) in Gabon in the 1990s, compared to neighboring countries, represents a paradox that led us to search for viral and human genetic variants in this country. In this study, only variants of coreceptors and chemokines were investigated.
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