CBX7 Expression in Oncocytic Thyroid Neoplastic Lesions (Hürthle Cell Adenomas and Carcinomas)
Author(s) -
Mario Monaco,
Gennaro Chiappetta,
Concetta Aiello,
Antonella Federico,
Romina Sepe,
Daniela Russo,
Alfredo Fusco,
Pierlorenzo Pallante
Publication year - 2014
Publication title -
european thyroid journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.23
H-Index - 10
eISSN - 2235-0802
pISSN - 2235-0640
DOI - 10.1159/000367989
Subject(s) - medicine , thyroid , adenoma , pathology , immunohistochemistry , thyroid carcinoma , cell , oncocytoma , follicular cell , cancer research , biology , genetics
Previous analysis of CBX7 expression in a large number of thyroid adenoma and carcinoma samples revealed a progressive reduction of CBX7 levels that was well related with the malignant grade of thyroid neoplasias. Hürthle cell tumors are unusual thyroid neoplasms characterized by the presence of particular cells called oncocytes.
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