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Correspondence of Plasma and Salivary Cortisol Patterns in Women with Breast Cancer
Author(s) -
Jamie M. Zeitzer,
Bita Nouriani,
Eric Neri,
David Spiegel
Publication year - 2014
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000367925
Subject(s) - circadian rhythm , morning , evening , medicine , endocrinology , cortisol awakening response , saliva , diurnal temperature variation , hydrocortisone , glucocorticoid , breast cancer , cancer , physics , atmospheric sciences , astronomy , geology
The 'diurnal slope' of salivary cortisol has been used as a measure of stress and circadian function in a variety of reports with several detailing its association with cancer progression. The relationship of this slope, typically a negative value from high morning concentrations to low evening concentrations, to the underlying daily variation in total plasma cortisol throughout the 24-hour cycle, however, has never been reported.

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