Insulin Influences Autophagy Response Distinctively in Macrophages of Different Compartments | Zendy

Karen K. S. Sunahara | Zendy; Fernanda Peixoto Barbosa Nunes | Zendy; Marisa A. P. Baptista | Zendy; Carina Strell | Zendy; Paulina Sannomiya | Zendy; Lisa S. Westerberg | Zendy; Joilson O. Martins | Zendy

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Insulin Influences Autophagy Response Distinctively in Macrophages of Different Compartments

Author(s) -

Karen K. S. Sunahara,

Fernanda Peixoto Barbosa Nunes,

Marisa A. P. Baptista,

Carina Strell,

Paulina Sannomiya,

Lisa S. Westerberg,

Joilson O. Martins

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366397

Subject(s) - bronchoalveolar lavage , insulin , cytokine , medicine , endocrinology , macrophage , proinflammatory cytokine , tumor necrosis factor alpha , inflammation , chemistry , biology , lung , biochemistry , in vitro

Diabetes mellitus (DM) is characterized by hyperglycemia, associated to a lack or inefficiency of the insulin to regulate glucose metabolism. DM is also marked by alterations in a diversity of cellular processes that need to be further unraveled. In this study, we examined the autophagy pathway in diabetic rat macrophages before and after treatment with insulin.

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