Mechanisms of RhoGDI2 Mediated Lung Cancer Epithelial-Mesenchymal Transition Suppression
Author(s) -
Huiyan Niu,
Baogang Wu,
Hongfang Jiang,
Hui Li,
Yi Zhang,
Peng Yang,
Ping He
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000366396
Subject(s) - epithelial–mesenchymal transition , rac1 , a549 cell , slug , vimentin , immunostaining , biology , cancer research , metastasis , microbiology and biotechnology , lung cancer , cell migration , pathology , cell , cancer , immunology , medicine , immunohistochemistry , signal transduction , genetics
The aim of this study was to evaluate the function of RhoGDI2 in lung cancer epithelial-mesenchymal transition (EMT) process and to illustrate the underlying mechanisms that will lead to improvement of lung cancer treatment.
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