Aberrant Hepatic MicroRNA Expression in Nonalcoholic Fatty Liver Disease
Author(s) -
Yue Feng,
Xiao Qin Xu,
Chen Bo Ji,
Chun Mei Shi,
Xi Rong Guo,
Jun Fu
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000366394
Subject(s) - microrna , proinflammatory cytokine , nonalcoholic fatty liver disease , steatosis , mir 122 , biology , fatty liver , insulin resistance , endocrinology , steatohepatitis , medicine , fold change , cancer research , gene expression , inflammation , immunology , disease , gene , obesity , genetics
Emerging evidence suggests that microRNA (miRNA) mediated gene regulation influences the maintenance of metabolic homeostasis, particularly the states of obesity and insulin resistance, thereby providing a potential link between miRNAs and nonalcoholic fatty liver disease (NAFLD).
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