Serum MiRNA Biomarkers serve as a Fingerprint for Proliferative Diabetic Retinopathy | Zendy

Qing Shao | Zendy; Songtao Yuan | Zendy; Yun Chen | Zendy; Hui Hang | Zendy; Pingan Mao | Zendy; Wen Fan | Zendy; Yuzhi Ding | Zendy; Qinghuai Liu | Zendy

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Serum MiRNA Biomarkers serve as a Fingerprint for Proliferative Diabetic Retinopathy

Author(s) -

Qing Shao,

Songtao Yuan,

Yun Chen,

Hui Hang,

Pingan Mao,

Wen Fan,

Yuzhi Ding,

Qinghuai Liu

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366374

Subject(s) - diabetic retinopathy , medicine , taqman , receiver operating characteristic , microrna , diabetes mellitus , oncology , real time polymerase chain reaction , bioinformatics , biology , endocrinology , gene , biochemistry

Diabetic retinopathy (DR) is a retinopathy resulting from diabetes mellitus (DM) which was classified into non-proliferative DR (NPDR) and proliferative DR (PDR). Without an early screening and effective diagnosis, patients with PDR will develop serious complications. Therefore, we sought to identify special serum microRNAs (miRNAs) that can serve as a novel non-invasive screening signature of PDR and test its specificity and sensitivity in the early diagnosis of PDR.

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