Connexin 43 is Involved in Aldosterone-Induced Podocyte Injury | Zendy

Min Yang | Zendy; Bin Wang | Zendy; Min Li | Zendy; Bo Jiang | Zendy

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Connexin 43 is Involved in Aldosterone-Induced Podocyte Injury

Author(s) -

Min Yang,

Bin Wang,

Min Li,

Bo Jiang

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366367

Subject(s) - podocyte , connexin , aldosterone , microbiology and biotechnology , chemistry , medicine , endocrinology , biology , gap junction , kidney , intracellular , proteinuria

Connexin43 (Cx43) belongs to a family of transmembrane proteins that build cell-to-cell channels in gap junctions, which play an essential role in intercellular communication, cell proliferation, differentiation and apoptosis. The aim of this study is to clarify the effect of Cx43 in aldosterone (Aldo)-induced podocyte injury and explore the possible molecular mechanism behind this effect.

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