Increased Susceptibility to Apoptosis and Growth Arrest of Human Breast Cancer Cells Treated by a Snake Venom-Loaded Silica Nanoparticles | Zendy

Gamal Badr | Zendy; Douaa Sayed | Zendy; Doaa Maximous | Zendy; Amany O. Mohamed | Zendy; Mustafa Gül | Zendy

Open Access

Increased Susceptibility to Apoptosis and Growth Arrest of Human Breast Cancer Cells Treated by a Snake Venom-Loaded Silica Nanoparticles

Author(s) -

Gamal Badr,

Douaa Sayed,

Doaa Maximous,

Amany O. Mohamed,

Mustafa Gül

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366366

Subject(s) - apoptosis , breast cancer , cancer research , cancer , cancer cell , cell cycle checkpoint , flow cytometry , medicine , cell cycle , cell growth , reactive oxygen species , chemistry , immunology , biochemistry

The development of effective treatments against metastatic cancers, including breast cancer, is among the most important challenges in current experimental and clinical cancer research. We recently demonstrated that Walterinnesia aegyptia venom (WEV), either alone or in combination with silica nanoparticles (WEV+NP), resulted in the growth arrest and apoptosis of different cancer cell lines.

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