Expression of Cre Recombinase in Alveolar Epithelial Cells of the AQP2-Cre Transgenic Mini-Pigs | Zendy

Weiwei Luo | Zendy; Zhanjun Li | Zendy; Peng Li | Zendy; Yongye Huang | Zendy; Yang Han | Zendy; Chaogang Yao | Zendy; Zhongzhan Zhang | Zendy; Honggang Yan | Zendy; Daxin Pang | Zendy; Hongsheng Ouyang | Zendy; Li Li | Zendy

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Expression of Cre Recombinase in Alveolar Epithelial Cells of the AQP2-Cre Transgenic Mini-Pigs

Author(s) -

Weiwei Luo,

Zhanjun Li,

Peng Li,

Yongye Huang,

Yang Han,

Chaogang Yao,

Zhongzhan Zhang,

Honggang Yan,

Daxin Pang,

Hongsheng Ouyang,

Li Li

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366363

Subject(s) - cre recombinase , transgene , biology , microbiology and biotechnology , aquaporin 2 , transfection , genetically modified mouse , gene , miniature pig , cell culture , genetics , mechanical engineering , water channel , engineering , inlet

Optimal use of Cre mediated recombination in conditional animal models depends on well characterized Cre driver lines. Unfortunately, some Cre driver lines exhibit unexpected expression patterns hindering their utility in Cre/loxP systems. Thus, systematic assessment of new Cre lines is essential for generating useful Cre driver lines for future studies.

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