MiR-23a Functions as a Tumor Suppressor in Osteosarcoma | Zendy

Yu He | Zendy; Chunqing Meng | Zendy; Zengwu Shao | Zendy; Hong Wang | Zendy; Shuhua Yang | Zendy

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MiR-23a Functions as a Tumor Suppressor in Osteosarcoma

Author(s) -

Yu He,

Chunqing Meng,

Zengwu Shao,

Hong Wang,

Shuhua Yang

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366353

Subject(s) - osteosarcoma , ectopic expression , cell growth , cancer research , microrna , biology , dna methylation , runx2 , reporter gene , in vivo , luciferase , transfection , microbiology and biotechnology , transcription factor , cell culture , gene expression , gene , genetics

Osteosarcoma is the most common primary bone malignancy in children and adolescents, and the pathogenesis of this cancer remains unclear. Therefore, the discovery of new biomarkers for the diagnosis, prognosis, and treatment of osteosarcoma remains an important but unmet clinical need.

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