CXCL1 Regulation in Human Pulmonary Epithelial Cells by Tumor Necrosis Factor | Zendy

JiunnMin Shieh | Zendy; YihJeng Tsai | Zendy; Chih-Jen Tsou | Zendy; WenBin Wu | Zendy

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CXCL1 Regulation in Human Pulmonary Epithelial Cells by Tumor Necrosis Factor

Author(s) -

JiunnMin Shieh,

YihJeng Tsai,

Chih-Jen Tsou,

WenBin Wu

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366344

Subject(s) - cxcl1 , mapk/erk pathway , protein kinase b , cancer research , p38 mitogen activated protein kinases , tumor necrosis factor alpha , chemokine , cytokine , pi3k/akt/mtor pathway , chemistry , biology , signal transduction , endocrinology , medicine , microbiology and biotechnology , immunology , inflammation

The chemokine CXCL1 has been reported to be expressed in lung airway epithelium and non-small cell lung cancer biopsy specimens. In this study, we investigated the effects of TNF-α, an abundant cytokine detected in inflammation and various cancers, on CXCL1 release by human A549 lung carcinoma epithelial cells.

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