Functional Characteristics of Reversibly Immortalized Hepatic Progenitor Cells Derived from Mouse Embryonic Liver
Author(s) -
Yang Bi,
Yun He,
Jiayi Huang,
Yuxi Su,
Gaohui Zhu,
Yì Wáng,
Min Qiao,
Bingqiang Zhang,
Hongyu Zhang,
Zhongliang Wang,
Wei Liu,
Jing Cui,
Quan Kang,
Zhonglin Zhang,
Youlin Deng,
Ruifang Li,
Qian Zhang,
Ke Yang,
Hue H. Luu,
Rex C. Haydon,
TongChuan He,
Ni Tang
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000366340
Subject(s) - progenitor cell , embryonic stem cell , biology , hepatocyte , foxa2 , microbiology and biotechnology , stem cell , liver cytology , progenitor , hepatic stellate cell , cancer research , endocrinology , in vitro , biochemistry , liver metabolism , gene
Liver is a vital organ and retains its regeneration capability throughout adulthood, which requires contributions from different cell populations, including liver precursors and intrahepatic stem cells. To overcome the mortality of hepatic progenitors (iHPs) in vitro, we aim to establish reversibly immortalized hepatic progenitor cells from mouse embryonic liver.
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