Co-Culture Systems of Human Sweat Gland Derived Stem Cells and Peripheral Nerve Cells: Anin VitroApproach for Peripheral Nerve Regeneration
Author(s) -
Julia M. Mehnert,
Tobias Kisch,
Matthias Brandenburger
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000366318
Subject(s) - neurite , regeneration (biology) , dorsal root ganglion , stem cell , microbiology and biotechnology , paracrine signalling , in vitro , biology , medicine , neuroscience , anatomy , dorsum , receptor , biochemistry
The treatment of peripheral nerve lesions still represents a clinical challenge. Several approaches such as novel biomaterials for nerve guides, addition of growth factors or cellular supplements moved in the focus of research. Especially the application of autologous stem cells is highly promising for future applications. Human sweat gland derived stem cells (hSGSCs) represent an easy accessible source of autologous adult stem cells and did already show a beneficial effect in dermal wound healing.
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