Characteristics of Gintonin-Mediated Membrane Depolarization of Pacemaker Activity in Cultured Interstitial Cells of Cajal | Zendy

Byung Joo Kim | Zendy; JooHyun Nam | Zendy; Kyun Ha Kim | Zendy; Myungsoo Joo | Zendy; Tal Soo Ha | Zendy; Kwon-Yeon Weon | Zendy; Seok Choi | Zendy; Jae Yeoul Jun | Zendy; EunJung Park | Zendy; Jinhong Wie | Zendy; Insuk So | Zendy; Seung-Yeol Nah | Zendy

Open Access

Characteristics of Gintonin-Mediated Membrane Depolarization of Pacemaker Activity in Cultured Interstitial Cells of Cajal

Author(s) -

Byung Joo Kim,

JooHyun Nam,

Kyun Ha Kim,

Myungsoo Joo,

Tal Soo Ha,

Kwon-Yeon Weon,

Seok Choi,

Jae Yeoul Jun,

EunJung Park,

Jinhong Wie,

Insuk So,

Seung-Yeol Nah

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000366306

Subject(s) - cystic fibrosis transmembrane conductance regulator , interstitial cell of cajal , chemistry , depolarization , activator (genetics) , apamin , chloride channel , purinergic receptor , medicine , endocrinology , calcium , microbiology and biotechnology , cystic fibrosis , biology , receptor , biochemistry , smooth muscle

Ginseng regulates gastrointestinal (GI) motor activity but the underlying components and molecular mechanisms are unknown. We investigated the effect of gintonin, a novel ginseng-derived G protein-coupled lysophosphatidic acid (LPA) receptor ligand, on the pacemaker activity of the interstitial cells of Cajal (ICC) in murine small intestine and GI motility.

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