A Ten-Year Retrospective Analysis of the Distribution, Use and Phenotypic Characteristics of the LAD2 Human Mast Cell Line | Zendy

Arnold S. Kirshenbaum | Zendy; Amy Petrik | Zendy; Rosemary Walsh | Zendy; Tara L. Kirby | Zendy; Sury Vepa | Zendy; Danny Wangsa | Zendy; Thomas Ried | Zendy; Dean D. Metcalfe | Zendy

Open Access

A Ten-Year Retrospective Analysis of the Distribution, Use and Phenotypic Characteristics of the LAD2 Human Mast Cell Line

Author(s) -

Arnold S. Kirshenbaum,

Amy Petrik,

Rosemary Walsh,

Tara L. Kirby,

Sury Vepa,

Danny Wangsa,

Thomas Ried,

Dean D. Metcalfe

Publication year - 2014

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000365729

Subject(s) - degranulation , mast cell , cell culture , immunology , medicine , receptor , chemistry , biology , genetics

In 2003, this laboratory published an account of the human mast cell line LAD2 (Laboratory of Allergic Diseases 2) that expressed FcεRI, responded to recombinant human stem cell factor (rhSCF) and resembled CD34+-derived human mast cells. LAD2 cells have now been distributed worldwide. To study the impact of this transfer, we analyzed the number of investigators receiving LAD2 cells and resulting publications.

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