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A Prospective Randomised Paired Trial of Sirolimus versus Tacrolimus as Primary Immunosuppression following Non-Heart Beating Donor Kidney Transplantation
Author(s) -
John Asher,
Nikhil Vasdev,
H. Wyrley-Birch,
Colin Wilson,
Naeem Soomro,
D. Rix,
Bryon Jaques,
Derek Manas,
Nicholas Torpey,
David Talbot
Publication year - 2014
Publication title -
current urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 13
eISSN - 1661-7657
pISSN - 1661-7649
DOI - 10.1159/000365671
Subject(s) - medicine , sirolimus , tacrolimus , calcineurin , immunosuppression , clinical endpoint , transplantation , urology , heart transplantation , kidney transplantation , surgery , randomized controlled trial
With calcineurin inhibitors potentiating damage from ischaemia-reperfusion injury in kidneys from donors after cardiac death we wanted to investigate the role of substituting sirolimus for tacrolimus in the delayed introduction of calcineurin inhibitor regime used in our centre.

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