Beyond GWAS in COPD: Probing the Landscape between Gene-Set Associations, Genome-Wide Associations and Protein-Protein Interaction Networks | Zendy

MerryLynn McDonald | Zendy; Manuel Mattheisen | Zendy; Michael H. Cho | Zendy; YangYu Liu | Zendy; Benjamin J. Harshfield | Zendy; Craig P. Hersh | Zendy; Per Bakke | Zendy; Amund Gulsvik | Zendy; Christoph Lange | Zendy; Terri H. Beaty | Zendy; Edwin K. Silverman | Zendy

Open Access

Beyond GWAS in COPD: Probing the Landscape between Gene-Set Associations, Genome-Wide Associations and Protein-Protein Interaction Networks

Author(s) -

MerryLynn McDonald,

Manuel Mattheisen,

Michael H. Cho,

YangYu Liu,

Benjamin J. Harshfield,

Craig P. Hersh,

Per Bakke,

Amund Gulsvik,

Christoph Lange,

Terri H. Beaty,

Edwin K. Silverman

Publication year - 2014

Publication title -

human heredity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.423

H-Index - 62

eISSN - 1423-0062

pISSN - 0001-5652

DOI - 10.1159/000365589

Subject(s) - genome wide association study , copd , genetic association , gene , candidate gene , biology , computational biology , genetics , bioinformatics , medicine , genotype , single nucleotide polymorphism

To use a systems biology approach to integrate genotype and protein-protein interaction (PPI) data to identify disease network modules associated with chronic obstructive pulmonary disease (COPD) and to perform traditional pathway analysis.

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