Hepatitis B Virus-Related Hepatocellular Carcinoma: Pathogenic Mechanisms and Novel Therapeutic Interventions
Author(s) -
Hongzhi Xu,
Yunpeng Liu,
Bayasi Guleng,
Jianlin Ren
Publication year - 2014
Publication title -
gastrointestinal tumors
Language(s) - English
Resource type - Journals
eISSN - 2296-3766
pISSN - 2296-3774
DOI - 10.1159/000365307
Subject(s) - hepatitis b virus , hepatocellular carcinoma , lamivudine , immunology , medicine , immunotherapy , hepatitis b , virus , virology , interferon , immune system , cancer research
Infection with the hepatitis B virus (HBV) is one of most important risk factors for hepatocellular carcinoma (HCC). Indeed, HBV is considered a group 1 human carcinogen and is a highly oncogenic agent. HBV cannot be effectively controlled or completely eliminated, so chronic HBV infection is a public health challenge worldwide.
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