Antihypertensive Medication Exposure and Cardiovascular Outcomes in Hemodialysis Patients | Zendy

Theresa I. Shireman | Zendy; Milind A. Phadnis | Zendy; James B. Wetmore | Zendy; Xinhua Zhou | Zendy; Sally K. Rigler | Zendy; John A. Spertus | Zendy; Edward F. Ellerbeck | Zendy; Jonathan D. Mahnken | Zendy

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Antihypertensive Medication Exposure and Cardiovascular Outcomes in Hemodialysis Patients

Author(s) -

Theresa I. Shireman,

Milind A. Phadnis,

James B. Wetmore,

Xinhua Zhou,

Sally K. Rigler,

John A. Spertus,

Edward F. Ellerbeck,

Jonathan D. Mahnken

Publication year - 2014

Publication title -

american journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 85

eISSN - 1421-9670

pISSN - 0250-8095

DOI - 10.1159/000365255

Subject(s) - medicine , hazard ratio , dialysis , proportional hazards model , clinical endpoint , cohort , hemodialysis , kidney disease , emergency medicine , intensive care medicine , clinical trial , confidence interval

Our understanding of the effectiveness of cardioprotective medications in maintenance dialysis patients is based upon drug exposures assessed at a single point in time. We employed a novel, time-dependent approach to modeling medication use over time to examine outcomes in a large national cohort.

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