Impact of Common Treatments Given in the Perinatal Period on the Developing Brain
Author(s) -
Géraldine Favrais,
Pierre Tourneux,
Emmanuel López,
Xavier Durrmeyer,
Géraldine Gascoin,
Duksha Ramful,
Elodie ZanaTaïeb,
Olivier Baud
Publication year - 2014
Publication title -
neonatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.399
H-Index - 84
eISSN - 1661-7819
pISSN - 1661-7800
DOI - 10.1159/000363492
Subject(s) - medicine , neuroprotection , brain damage , neurocognitive , pediatrics , periventricular leukomalacia , intensive care medicine , anesthesia , pregnancy , gestational age , cognition , psychiatry , biology , genetics
Over the last decades, considerable progress has been made in the perinatal management of high-risk preterm neonates, changing the landscape of pathological conditions associated with neurological impairments. Major focal destructive lesions are now less common, and the predominant neuropathological lesion is diffuse white-matter damage in the most immature infants. Similarly, over the last few years, we have observed a trend towards a decrease in neurological impairment in the absence of treatments specifically aimed at neuroprotection.
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