Transfusion Efficacy of Apheresis Platelet Concentrates Irradiated at the Day of Transfusion Is Significantly Superior Compared to Platelets Irradiated in Advance | Zendy

Friedgard Julmy | Zendy; Roland A. Ammann | Zendy; Stefano Fontana | Zendy; Behrouz Mansouri Taleghani | Zendy; Andreas Hirt | Zendy; Kurt Leibundgut | Zendy

Open Access

Transfusion Efficacy of Apheresis Platelet Concentrates Irradiated at the Day of Transfusion Is Significantly Superior Compared to Platelets Irradiated in Advance

Author(s) -

Friedgard Julmy,

Roland A. Ammann,

Stefano Fontana,

Behrouz Mansouri Taleghani,

Andreas Hirt,

Kurt Leibundgut

Publication year - 2014

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000363484

Subject(s) - medicine , apheresis , platelet , blood irradiation therapy , irradiation , whole blood , pathology , nuclear physics , physics , alternative medicine

Gamma irradiation is currently the standard care to avoid transfusion-associated graft-versus-host disease. Guidelines on gamma irradiation of blood components state that platelets (PLTs) can be irradiated at any stage in their 5-day storage and can thereafter be stored up to their normal shelf life of 5 days after collection. In this study, we explored whether the timing of irradiation has an effect on transfusion efficacy of apheresis PLT concentrates (APCs).

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