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Urinary Excretion of Melatonin and Association with Breast Cancer: Meta-Analysis and Review of the Literature
Author(s) -
Michelle Basler,
Alexander Jetter,
Daniel Fink,
Burkhardt Seifert,
Gerd A. KullakUblick,
Andreas Trojan
Publication year - 2014
Publication title -
breast care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.767
H-Index - 30
eISSN - 1661-3805
pISSN - 1661-3791
DOI - 10.1159/000363426
Subject(s) - melatonin , medicine , endocrinology , meta analysis , endocrine system , pineal gland , hormone , physiology
Melatonin is an endocrine hormone secreted by the pineal gland during night hours that provides several biological functions in the circadian rhythm of humans. Due to anti-estrogenic properties, melatonin is considered to exhibit a protective role against the development of breast cancer (BC). Moreover, disruption of melatonin production through environmental influences, such as night work, is assumed to be a risk factor for BC.

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