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New Inhaler Devices - The Good, the Bad and the Ugly
Author(s) -
Federico Lavorini,
Giovanni Fontana,
Omar S. Usmani
Publication year - 2014
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000363390
Subject(s) - medicine , dry powder inhaler , inhaler , copd , asthma , intensive care medicine , pulmonary disease , metered dose inhaler , drug delivery , drug , pharmacology , chemistry , organic chemistry
Drug delivery to the lungs is an effective way of targeting inhaled therapeutic aerosols and treating obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). In the past 10 years, several new drugs for the management of asthma and COPD have been marketed and more are under development. These new therapeutic respiratory drugs have been furthered by innovations in all categories of pulmonary drug delivery systems to ensure optimal aerosolisation performance, consistency in efficacy and satisfactory patient adherence. In this review, we discuss the technological advances and innovations in recent inhaler devices and the evolving roles of pressurised metered-dose inhalers, dry powder inhalers and nebulisers, as well as their impact on patient adherence to treatment.

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