Decreased MiR-200a/141 Suppress Cell Migration and Proliferation by Targeting PTEN in Hirschsprung's Disease | Zendy

Hongxing Li | Zendy; Junwei Tang | Zendy; Lei Hao | Zendy; Peng Cai | Zendy; Hairong Zhu | Zendy; Bo Li | Zendy; Xiaoqun Xu | Zendy; Yankai Xia | Zendy; Weibing Tang | Zendy

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Decreased MiR-200a/141 Suppress Cell Migration and Proliferation by Targeting PTEN in Hirschsprung's Disease

Author(s) -

Hongxing Li,

Junwei Tang,

Lei Hao,

Peng Cai,

Hairong Zhu,

Bo Li,

Xiaoqun Xu,

Yankai Xia,

Weibing Tang

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000363021

Subject(s) - pten , microrna , cell growth , biology , cancer research , pathogenesis , flow cytometry , reporter gene , hek 293 cells , viability assay , western blot , hirschsprung's disease , cell migration , microbiology and biotechnology , cell , pi3k/akt/mtor pathway , cell culture , gene expression , signal transduction , gene , medicine , immunology , pathology , disease , genetics

Hirschsprung's disease (HSCR) is a genetic disorder of neural crest development. In this study, we investigated whether and how miR-200a and miR-141, belonging to miR-200 family, were involved in the pathogenesis of HSCR.

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