Parity and Short-Term Estradiol Treatment Utilizes Similar Cellular Mechanisms to Confer Protection Against Breast Cancer | Zendy

Arunkumar Arumugam | Zendy; Ramadevi Subramani | Zendy; Sushmita Nandy | Zendy; Rebecca Lopez | Zendy; Thiyagarajan Boopalan | Zendy; Rajkumar Lakshmanaswamy | Zendy

Open Access

Parity and Short-Term Estradiol Treatment Utilizes Similar Cellular Mechanisms to Confer Protection Against Breast Cancer

Author(s) -

Arunkumar Arumugam,

Ramadevi Subramani,

Sushmita Nandy,

Rebecca Lopez,

Thiyagarajan Boopalan,

Rajkumar Lakshmanaswamy

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000363017

Subject(s) - biology , estrogen receptor , endocrinology , mammary gland , receptor , medicine , estrogen , cell growth , cancer research , breast cancer , cancer , biochemistry

Protective effect of early pregnancy and short-term estrogen treatment (STET), against breast cancer is well established. The underlying mechanisms are not well understood. In this study, we compared the mammary gland cellular microenvironment influenced/induced by parity and STET alongside age-matched controls.

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