MCP-1 Stimulates MMP-9 Expression via ERK 1/2 and p38 MAPK Signaling Pathways in Human Aortic Smooth Muscle Cells
Author(s) -
Ci-Qiu Yang,
Wen Li,
Songqi Li,
Jie Li,
Yuwen Li,
Shu-Xin Kong,
Rui-Ming Liu,
Shenming Wang,
Weiming Lv
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000362997
Subject(s) - mapk/erk pathway , p38 mitogen activated protein kinases , kinase , signal transduction , protein kinase a , microbiology and biotechnology , mitogen activated protein kinase , matrix metalloproteinase , chemistry , vascular smooth muscle , biology , endocrinology , biochemistry , smooth muscle
We investigated the molecular mechanism underlying the role of monocyte chemoattractant protein-1 (MCP-1) in the formation and development of human abdominal aortic aneurysm (AAA).
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