Interaction of Amorphous Silica Nanoparticles with Erythrocytesin Vitro: Role of Oxidative Stress
Author(s) -
Abderrahim Nemmar,
Sumay Beegam,
Priya Yuvaraju,
Javed Yasin,
Allen Shahin,
Badreldin H. Ali
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000362996
Subject(s) - oxidative stress , lipid peroxidation , nanotoxicology , chemistry , glutathione , malondialdehyde , superoxide dismutase , catalase , biochemistry , lactate dehydrogenase , in vivo , in vitro , pharmacology , biology , toxicity , enzyme , microbiology and biotechnology , organic chemistry
The use of engineered nanomaterials in the form of nanoparticles (NP) for various biomedical applications, as well as in consumer products, has raised concerns about their safety for human health. These NP are intended to be administered directly into the circulation following intravenous injection, or they may reach the circulation following other routes of administration such as oral or inhalation, and interact with circulating cells such as erythrocytes. However, little is known about the interaction of amorphous SiNP with erythrocytes.
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