HDL-Bound Sphingosine 1-Phosphate (S1P) Predicts the Severity of Coronary Artery Atherosclerosis | Zendy

Katherine Sattler | Zendy; Isa Lehmann | Zendy; Markus H. Gräler | Zendy; Martina BröckerPreuß | Zendy; Raimund Erbel | Zendy; Gerd Heusch | Zendy; Bodo Levkau | Zendy

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HDL-Bound Sphingosine 1-Phosphate (S1P) Predicts the Severity of Coronary Artery Atherosclerosis

Author(s) -

Katherine Sattler,

Isa Lehmann,

Markus H. Gräler,

Martina BröckerPreuß,

Raimund Erbel,

Gerd Heusch,

Bodo Levkau

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000362993

Subject(s) - medicine , coronary artery disease , restenosis , cardiology , conventional pci , stenosis , percutaneous coronary intervention , lesion , radiology , myocardial infarction , surgery , stent

We have recently demonstrated a reduction in HDL-bound sphingosine 1-phosphate (S1P) in patients with stable coronary artery disease (CAD). In the current study, we tested whether HDL-associated S1P is predictive for the degree of coronary stenosis, restenosis and overall CAD severity on follow up in patients undergoing elective percutaneous coronary intervention (PCI).

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