Sex-Dependent Decrease of Sphingomyelinase Activity During Alcohol Withdrawal Treatment | Zendy

Christiane Mühle | Zendy; Violina Amova | Zendy; Teresa Biermann | Zendy; Kristina Bayerlein | Zendy; Tanja RichterSchmidinger | Zendy; Thomas Kraus | Zendy; Martin Reichel | Zendy; Erich Gulbins | Zendy; Johannes Kornhuber | Zendy

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Sex-Dependent Decrease of Sphingomyelinase Activity During Alcohol Withdrawal Treatment

Author(s) -

Christiane Mühle,

Violina Amova,

Teresa Biermann,

Kristina Bayerlein,

Tanja RichterSchmidinger,

Thomas Kraus,

Martin Reichel,

Erich Gulbins,

Johannes Kornhuber

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000362985

Subject(s) - acid sphingomyelinase , beck depression inventory , craving , medicine , depression (economics) , endocrinology , alcohol dependence , biomarker , body mass index , ethanol , alcohol , psychiatry , sphingomyelin , cholesterol , biology , anxiety , addiction , biochemistry , economics , macroeconomics

In vitro and in vivo studies have demonstrated the role of the acid sphingomyelinase (ASM) in pathophysiological processes and alterations in response to ethanol exposure. Cellular and plasmatic ASM activities are increased in male alcohol dependent patients and decrease during physical withdrawal.

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