Open AccessInvariant Natural Killer T (iNKT) Cells Prevent Autoimmunity, but Induce Pulmonary Inflammation in Cystic Fibrosis
Author(s) -
Nanna Siegmann,
David Worbs,
Frauke Effinger,
Tobias Bormann,
Madlen Gebhardt,
Martina Ulrich,
Fredrik Wermeling,
Eva MüllerHermelink,
Tilo Biedermann,
Mike Tighe,
Michael J. Edwards,
Charles C. Caldwell,
Elizabeth A. Leadbetter,
Mikael C. I. Karlsson,
Katrin Anne Becker,
Erich Gulbins,
Gerd Döring
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000362984
Subject(s) - cystic fibrosis , inflammation , immunology , autoimmunity , medicine , fibrosis , lung , immune system , cytokine , pathology
Inflammation is a major and critical component of the lung pathology in the hereditary disease cystic fibrosis. The molecular mechanisms of chronic inflammation in cystic fibrosis require definition.
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