Open AccessCaffeine Inhibits Migration in Glioma Cells through the ROCK-FAK Pathway
Author(s) -
Ying Chen,
Wei-Chung Chou,
Youming Ding,
Ya-Chieh Wu
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000362966
Subject(s) - paxillin , focal adhesion , cell migration , glioma , microbiology and biotechnology , chemistry , myosin light chain kinase , cancer research , myosin , caffeine , rho associated protein kinase , kinase , biology , phosphorylation , cell , biochemistry , endocrinology
Glioma is the most malignant brain tumor that has the ability to migrate and invade the CNS. In this study, we investigated the signaling mechanism of caffeine on the migration of glioma cells.
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