Ox-LDL Influences Peripheral Th17/Treg Balance by Modulating Treg Apoptosis and Th17 Proliferation in Atherosclerotic Cerebral Infarction | Zendy

Qing Li | Zendy; Yiping Wang | Zendy; HongQi Li | Zendy; Guodong Shen | Zendy; Shilian Hu | Zendy

Open Access

Ox-LDL Influences Peripheral Th17/Treg Balance by Modulating Treg Apoptosis and Th17 Proliferation in Atherosclerotic Cerebral Infarction

Author(s) -

Qing Li,

Yiping Wang,

HongQi Li,

Guodong Shen,

Shilian Hu

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000362963

Subject(s) - apoptosis , pyrrolidine dithiocarbamate , fas ligand , downregulation and upregulation , immunology , chemistry , cancer research , endocrinology , medicine , nf κb , programmed cell death , biochemistry , gene

CD4(+)CD25(+) regulatory T (Treg) cells and T-helper 17 (Th17) cells play important roles in acute cerebral infarction (ACI). Our previous findings have suggested that oxidized low-density lipoprotein (Ox-LDL) could influence Treg/Th17 ratio in ACI patients. However, the mechanisms are still not clear.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research