The Predominant Pathway of Apoptosis in THP-1 Macrophage-Derived Foam Cells Induced by 5-Aminolevulinic Acid-Mediated Sonodynamic Therapy is the Mitochondria-Caspase Pathway Despite the Participation of Endoplasmic Reticulum Stress
Author(s) -
Huan Wang,
Yang Yang,
Haibo Chen,
Juhua Dan,
Jiali Cheng,
Shuyuan Guo,
Xin Sun,
Wei Wang,
Yiwei Ai,
Shuchang Li,
Zhixin Li,
Li Peng,
Zhen Tian,
Liming Yang,
Jichao Wu,
Xin Zhong,
Qi Zhou,
Peng Wang,
Zhiguo Zhang,
Wenwu Cao,
Ye Tian
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000362958
Subject(s) - sonodynamic therapy , apoptosis , unfolded protein response , cytochrome c , endoplasmic reticulum , mitochondrion , microbiology and biotechnology , apoptosome , downregulation and upregulation , caspase , caspase 12 , chemistry , thp1 cell line , intrinsic apoptosis , reactive oxygen species , caspase 9 , annexin , biology , biochemistry , programmed cell death , cell culture , genetics , gene
In advanced atherosclerosis, chronic endoplasmic reticulum (ER) stress induces foam cells apoptosis and generates inflammatory reactions.
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