Open Access(Epi)Genetic Analyses of Age-Related Macular Degeneration: Case-Control and Discordant Twin Studies
Author(s) -
John N. Hutchinson,
Jes Fagerness,
Andrew Kirby,
Robyn Reynolds,
Alex Zak,
Alexander A. Gimelbrant,
Robert M. Plenge,
Mark J. Daly,
Andrew Chess,
Johanna M. Seddon
Publication year - 2014
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000362814
Subject(s) - macular degeneration , twin study , genetics , biology , medicine , ophthalmology , heritability
Phenotypic discordance in monozygotic (MZ) twin pairs can have an epigenetic or genetic basis. Although age-related macular degeneration (AMD) has a strong genetic component, few studies have addressed its epigenetic basis.
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