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Considering the lack of accurate and up-to-date information available about neural tube defects (NTDs) in France, the purpose of this study was to review clinical and epidemiological data of NTDs and to evaluate the current efficiency of prenatal diagnosis in Alsace (northeastern France).

Neural Tube Defects: The Experience of the Registry of Congenital Malformations of Alsace, France, 1995-2009