SPARKLE (Subtypes of Ischaemic Stroke Classification System), Incorporating Measurement of Carotid Plaque Burden: A New Validated Tool for the Classification of Ischemic Stroke Subtypes | Zendy

Chrysi Bogiatzi | Zendy; Thapat Wannarong | Zendy; A. Ian McLeod | Zendy; Marnin J. Heisel | Zendy; Daniel G. Hackam | Zendy; J. David Spence | Zendy

Open Access

SPARKLE (Subtypes of Ischaemic Stroke Classification System), Incorporating Measurement of Carotid Plaque Burden: A New Validated Tool for the Classification of Ischemic Stroke Subtypes

Author(s) -

Chrysi Bogiatzi,

Thapat Wannarong,

A. Ian McLeod,

Marnin J. Heisel,

Daniel G. Hackam,

J. David Spence

Publication year - 2014

Publication title -

neuroepidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.217

H-Index - 87

eISSN - 1423-0208

pISSN - 0251-5350

DOI - 10.1159/000362417

Subject(s) - medicine , stroke (engine) , etiology , stenosis , ischemic stroke , acute stroke , cardiology , reliability (semiconductor) , ischemia , mechanical engineering , tissue plasminogen activator , engineering , power (physics) , physics , quantum mechanics

Previous classification systems of acute ischemic stroke (Causative Classification System, CCS, of acute ischemic stroke, Trial of Org 10172 in Acute Stroke Treatment, TOAST) established the diagnosis of large artery disease (LAD) based on the presence or absence of carotid stenosis. However, carotid plaque burden is a stronger predictor of cardiovascular risk than stenosis. Our objective was to update definitions of ischemic stroke subtypes to improve the detection of LAD and to assess the validity and reliability of a new classification system: SPARKLE (Subtypes of Ischaemic Stroke Classification System).

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